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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '25a722dc6b4eee2713e92716abc4594e517f3d0f41fc2f68ba372317f52e40cf' 
  AND token = 'GySaG8c2coa0j/NPvRK3LpaGV7uB7rwK5LNHIkrGnNM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}