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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '495d6318f771a6f0bc9c48306584b47da1b06a493d16f73fb9db9af5161a4432' 
  AND token = 'udz9n0qEZWROE1THc2IaQjMzrXTq/3cKhFchB68/bm4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}