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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7fe97c8696dc2cb01413d43a7985a83abf26315b69eb3ef8e4ceccb410143566' 
  AND token = '4Tv1sMGRL00KpmdgrT+r7I348wm7UmDOIXHSJWTTngs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}