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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd864aec56439dc816411286a76b241bd843b55596b07bd434e1306bd81df95f6' 
  AND token = 'v5cmMtADx8I0VGXeZjMxRqIU+PU7JhYAGkHTDdfIldk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}