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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '372999dbc00b234357abad3aa494ab611a66108c07750644730e220622993267' 
  AND token = 'bqtY5gi0pRp50ZKi6+mtF/Zj3kFNkvAvxgYXwNNFgd8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}