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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8608af9470580bcffc5ea189bbafe943815ed9c5933ab9f7783b8d8fe46a5804' 
  AND token = 'GV7IKF+cx2sYTjaztn8W+LcRHwsWAm/GE6D54NRYj+0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}