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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '91a6d04d7d44c681fad394281ed478872a57640b75a45a278007bd417489c98f' 
  AND token = 'Ose/twkQ79RmrHSl478jdVYirI6aC7xDwlOtc0MhSls=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}