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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cdf3daa7ef1a8edc6e350e356d66d7cd2b083760b76f3120b0c4d994fb422eba' 
  AND token = 'RLk/pHmbbJl+ZBEB2W+sKJPF4sGsoYI1BfAlcZ0WXME=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}