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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2547c3c03d192d3070b72d8075329ef2e27904c7010038cc76822cd1770b7d09' 
  AND token = 'S4HBOIBs9FFeMIQl3kDzRyHGvX0r6w4cYIyUlKMNTHk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}