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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5a8e0cee3b4753180b579849192b779aea6bc1f21232436d7829d8917033929b' 
  AND token = '5x02bj6XeNlo8v+K0O/4joF1c/S7QewCGIYsMXUZAnQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}