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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1a61c8af4e3bb18bb6708d40983d06a57e250b82bd590b6bcfec68ccf83df263' 
  AND token = 'JUVSWPLB9XUJF/lR4PqGXzV4LUF9QfawQlQBdy0cyT8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}