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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fe562bda36fbe89e8c8e5e2ca1dfbf7507ce860c38e6737697459c21477a1ad9' 
  AND token = 'Tx+VBy7Hn73AI1vNA0M8HLkVSU2HeXo2lJO8Li5dHs4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}