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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '081f2651d73deee39b419b9b1d027090dc6e545f03784f9a34eb466c3da63aee' 
  AND token = '6JLy5w56+Ff4jmNQ6rdisO0xOW8M9jfLSJc4ehyez5M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}