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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '50227ba355ec1bcd35f83b4c073cea75a45c217bdea7b2c1925bd2bc56c13afc' 
  AND token = 'K3mD7E6+G6RP1ppX6FqyUqHxKWIgoYtxL9dAZ/hN2Bo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}