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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '38d026e88de3eeb28d585dfa4c3e231346326eab669876f4d3ff8742b4d1f3bd' 
  AND token = 'L5Ji9lQtGWm9EXWvTh05cfCHzn2MLN2jsHotNCOqihM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}