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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8427b674e7ab86e8feebeab0f8eeaaf0ab2c2dd8550b2784b5278f8d05632ca7' 
  AND token = 'LMFm/OQT8p+3SojoO0kLlKj9ru9Vd1Q1MiPoCnoXdgo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}