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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c277b771efa88340f89384766fabfdf42bcc60e93e22e8f01266ed065172fd6c' 
  AND token = 'OeAnx5jVOok98OUGW4ENRK380YKmKWTZ0jIw1ZrHWpA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}