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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '48bc21ac55c9b4079e2f23521484a19de32ece97912751e1294b8ca5e827476e' 
  AND token = 'Xq9hea0ryXmqJ2d/jshuhWIYtV2p9ogFAbD8BLz9NUE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}