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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e6d493cc3cf2f38282cdfcdd25a1d619986325b09bfa1c2fdc40f3da09bd8b08' 
  AND token = 'aCfg4XFNxoffLOmLk0wxHX0RZkXYNvYMafMRgstrmr8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}