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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '421d1458a044a9c00f39deb1103a6e45cd71671e577b7c91a6fcc93244f10518' 
  AND token = 'j8bON82gtR4Q/2cH6Vcvv1GVHxwlBlwlcIUyw663c80=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}