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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1f74b990ce03508b6f8b31b389b15a43c1c02df75e10f15aa32dc11f4f3c9308' 
  AND token = 'SAIXd7OHr9GlqwCudRjIyjYTeIhEtrVQvPoLiGFCb8s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}