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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '64a81f40d00897d8af6bfa1b4ee6b485263eefc45295a7a57ec69960564b1667' 
  AND token = '4pV2w0n1pjB+5VVO7772Jorvnl2BwKDWyAQwhkk/ax4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}