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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '527d92b0011946b13f60178b0acd2a16e5592a150aacec110807d7a2fff7768b' 
  AND token = 'wXuMMc/DYVvBEOb/S2xdrzfRBGLiGtUMyMbejMc3/Wk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}