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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f6504edc8c5a23a38f4b7e8c40b62290ff5e53ad784e92a909c9db7698a04b02' 
  AND token = 'ctWVVHcmdtWn488BiUlKx5aIjKMuhKz+Kq5KUlC29Xs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}