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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5e67ca0e9c82678b6eb70c8625e7b5acca345b2a1f05844a3b336a4b12b60874' 
  AND token = 'wmF8itWwPAhAVbISEr4V/FZFB3K2ov5RH5FXR31oPGw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}