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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0cb3f98d3474a91f4efc548c01e3dd92ab57016ce094a0a387e8d3deb09be87c' 
  AND token = 'CQ/ADcDzw8I+rSQkGZOf+v2i/iBdUWiUKObSXlGH2xE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}