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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7a8ed1785a9018bf44b34189cb92d8e19fee9f67cf157db9f6c5aefdc29d27f5' 
  AND token = '2TxBvMCwf8rX7o5PbT4/fkAzr0/Eym0KxCBxZ0kEAls=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}