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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4aaebbb6f38cb13a702283006226ca5ef7488bdc439ec2ba5b34b930c8aa33fe' 
  AND token = '/Tcz18FL3lyPTsNnLsFfqzDD2sdV2gK4rLA/8SdUM5A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}