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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '80905690e2c9c7da64518037c3039c67dfc19846b2ba19b10d58cf8645f67cc0' 
  AND token = 'we5Enwf013wcSoUQ8WdXfxcZU4WpRfi7SiqVIXLXBxU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}