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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '58a84f0555a418c5144c2c3f4be07f8ecc5635b5df5db14bfad6b2010355aca4' 
  AND token = '7DFpa75ZHf2Zq+gDb4aQnBTk3LuV6di4qJ/uo7D9IAc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}