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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6d7fc956ddea3de402fb1a849f327d78ab295234705a35367e1d4c57dbd7a1b6' 
  AND token = 'R7EMcBJTpk0gvbaWHbUm6lj6hc5kYMRd947Q0h4eSKo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}