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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7dbd54d57cd19d3e693c52e3925664aa4c6eb956cbde50ba314e83dada1ac300' 
  AND token = '/vEsBpBqIGs2SwLQ7gU7Bk408yYadz0kQ3piWp2lZwQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00054

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}