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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '152ff4c9a89d0308e85d2ac7515737a3d1202f70b5fa06c8996dbb62ad2f03f8' 
  AND token = 'WCrqexqdaX+SlDMbd1E3DtPsk8sZWkJaLli069JqnCY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}