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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1a0fc89ad0def020260a22d4f395e9f52314e1d7fc9da39274a87ec6e22390de' 
  AND token = 'Z8uZyWU9rC2K3Uy5ypJa4Ep1OXy39mOwR6F3abR9CWs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}