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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '17f1f28e3773e1bab30618b8280405228ed1124b6f1af27620711ab4a85cbc1e' 
  AND token = '5XT1Lwir+WHnAXB2bf2DXEpE22BoYvkFserG1OVPxrE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}