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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e926e5eae3d451b8df3e9e667db3bd056d6337c3b570c9af31e40b864bbdd9b3' 
  AND token = '78HBqfs4pLg1Xh6pLTwwPZUEHw/+2JfSKZWnBO8OkUE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}