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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '22a7866c128bfa5f0d452bc3efd025c6607648d796b42c1e1268e9d614b8d246' 
  AND token = '2XAWl0nFXaPLYP2aP3lLuogfQmOsq2B/BZ2RyWNZb74=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00040

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}