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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '09169475f45a2bc783d5a7d3c1271dd915058e5f9db71cf78da76ffbc7b348ec' 
  AND token = 'mcC7uPCEwWldXZ47tGQ//lJ72Y8dEUgSzfVDnopFbio=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}