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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1653dad76a90d754eb0c0fda666c9f8c84b5f880b38a331045b14466ed030eae' 
  AND token = 'McWDlN+vdkBNNIcfjo3KOdGzPSR/5fHo65xH1m5mA6A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}