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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '15c5a22e7c4a56c5744367f1bb6504d1e39e20dff080a33526b2f283a1b5352f' 
  AND token = 'Yln2XYMz42un2aXBYvp7zoUXPVE4mA8YEJTXdBRs980=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}