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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ab57cdefe6638e0dc5e59c15738e761f4f21a217f3e8e1789951cf6173fc1f30' 
  AND token = 'mHBKdL8LuLg2g+JHJWu3oW6F1QEOWgWqBdbsZBIt7ZE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}