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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e8e44241891d583115133a17ab24204bb1cf742b046522a1647a04c870be8d0b' 
  AND token = 'ZBkkFI2+9EU8NKn980g1mUqeBXB3HLxMWAqWwwuHjgM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}