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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '756f59fdfc24c1f4d43bc5a64f049a84f940e969e51bd6f1854bea1c732c9504' 
  AND token = 'hxRG8kACVCfCXK5OZxCxoU4o1Rv1pm87VNe0ypCLgLY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}