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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6b5287a1d4cef836dc564577683dfdf51b2dbc67633f484d3888333813cc16a0' 
  AND token = 'uPm02PUnqG1ilHbBhaDxFkpAnwUG92FGeyusiXqC3eU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}