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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '33cda4bc968d09cbe71549914e194e5ad40a052cddb07665c848a96369e73499' 
  AND token = 'gr0BDX2X5HXXp1YkoHZ23oJ36AFiZze/SBTG3AQcHEQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}