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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2f6451e85fd08c136cf466a6dc0838bd58073166baf0ab0ddeffd66fe0599b1d' 
  AND token = 'LF05uJIHD8NT1t6rjdQ8rp/IeR7RsFTDJUtV0a+2zdk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}