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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e1a52c8a53e00041e3b9947772048c8c1728116fec56f387f53ad0fc12da8c50' 
  AND token = 'Yx1eS/2jIptNmvx3dGQZDKUsFHy7znkM/ysxpwXYRRw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}