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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b64da8dd21dad6435b8949c13a62161be0d00413035fdf2fe04ba0c9a2f9aee2' 
  AND token = 'V2mNmJQDGBYo6jSIkqI4cDZG+imQ5XF1RU59loaDvY4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}