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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '06360f5dc51d03bcd043261da2f7a774f0da64a50bc3c8ac399446c84f432805' 
  AND token = 'tZDmzT2RL6k9uz4Q3Fd4eWXJ2cInugjQtx0eUutvJHA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}