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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '43e5cef9eec0463a8010ac4802eac2efef440f1af2071a397c58161d713a527a' 
  AND token = 'Y0CEh1c0GFn9+ruBvVxg7jbGnec/JzYiS7ZRpMBW3JE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}